Binding of an imidazopyridoindole at imidazoline I2 receptors

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

Life Sciences, Biochemistry, Chemical Kinetics +14

Central cardiovascular effects of alpha adrenergic drugs: differences between catecholamines and imidazolines.

Pascal Bousquet, James A. Feldman, J. Schwartz · Journal of Pharmacology and Experimental Therapeutics · 1984 · 513 citations

Medicine, Neuroscience, Pharmacology +10

β-carboline binding to imidazoline receptors

Stephen M. Husbands, Richard A. Glennon, Stephane Gorgerat et al. · Drug and Alcohol Dependence · 2001 · 124 citations

Medicine, Medicinal Chemistry, Pharmacology +12

880. Tryptamines, carbolines, and related compounds. Part II. A convenient synthesis of tryptamines and β-carbolines

R. A. Abramovitch, David J. Shapiro · Journal of the Chemical Society (Resumed) · 1956 · 80 citations

Natural Sciences, Biochemistry, Chemistry +2

Imidazoline receptors: Qualitative structure-activity relationships and discovery of tracizoline and benazoline. Two ligands with high affinity and unprecedented selectivity

Maria Pigini, Pascal Bousquet, Angelo Carotti et al. · Bioorganic & Medicinal Chemistry · 1997 · 60 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14