Concepedia
Heart and Vessels · 2010 · 49 citations · 55 references
ThrombosisAdult Turkish PopulationCardiovascular DiseaseGenetic EpidemiologyHuman PolymorphismVkorc1 Genetic PolymorphismPharmacogenomicsPharmacotherapyPublic HealthMedicineWarfarin Dose RequirementsEpidemiology
55
Effect of <i>VKORC1</i> Haplotypes on Transcriptional Regulation and Warfarin Dose
Mark J. Rieder, Alexander P. Reiner, Brian F. Gage et al. · New England Journal of Medicine · 2005 · 1.4K citations · Full text
Association of polymorphisms in the cytochrome P450 CYP2C9 with warfarin dose requirement and risk of bleeding complications
Guruprasad P. Aithal, Christopher P. Day, Patrick Kesteven et al. · The Lancet · 1999 · 1.2K citations
Thrombosis, Medicine, Genetic Epidemiology +12
Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2
Simone Rost, Andreas Fregin, Vytautas Ivaškevičius et al. · Nature · 2004 · 1.1K citations
Thrombosis, Disease Mechanism, Genetic Disorder +10
Adjusted-dose warfarin versus low-intensity, fixed-dose warfarin plus aspirin for high-risk patients with atrial fibrillation: Stroke Prevention in Atrial Fibrillation III randomised clinical trial
The Lancet · 1996 · 1.1K citations · Full text
Association Between CYP2C9 Genetic Variants and Anticoagulation-Related Outcomes During Warfarin Therapy
Mitchell K. Higashi · JAMA · 2002 · 1.1K citations