Concepedia

Warfarin Resistance

Warfarin Resistance is a genetic-based insensitivity to the anticoagulant effects of warfarin in rodents, wherein affected individuals possess mutations in the vitamin K epoxide reductase complex subunit 1 (VKORC1) gene that diminish warfarin’s inhibitory action, thus preventing lethal hemorrhage despite exposure.

363

Publications

19.3K

Citations

1.5K

Authors

552

Institutions

Publications per year

2017–2026

30

Parents

Publications

363

Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2

Simone Rost, Andreas Fregin, Vytautas Ivaškevičius et al. · Nature · 2004 · 1.1K citations

, , +12

A non-canonical vitamin K cycle is a potent ferroptosis suppressor

Eikan Mishima, Junya Ito, Zijun Wu et al. · Nature · 2022 · 680 citations · Full text

, , +17

CYP4F2 genetic variant alters required warfarin dose

Michael D. Caldwell, Tarif Awad, Julie A. Johnson et al. · Blood · 2008 · 522 citations · Full text

, , +11

A novel functional VKORC1 promoter polymorphism is associated with inter-individual and inter-ethnic differences in warfarin sensitivity

Hsiang‐Yu Yuan, Jin‐Jer Chen, M.T. Michael Lee et al. · Human Molecular Genetics · 2005 · 489 citations

, , +14

Influence of cytochrome P-450 CYP2C9 polymorphisms on warfarin sensitivity and risk of over-anticoagulation in patients on long-term treatment

Janis M. Taube, David Halsall, Trevor Baglin · Blood · 2000 · 381 citations

, , +16

1–5 of 363

Authors

1.5K

  1. JH
    J. H. Greaves

    Tolworth Hospital, United Kingdom

    11 publications · 407 citations

    11

    h-index

  2. HP
    Hans‐Joachim Pelz

    Julius Kühn-Institut, Germany

    11 publications · 2K citations

    11

    h-index

  3. SR
    Simone Rost

    University of Würzburg, Germany

    9 publications · 2K citations

    9

    h-index

  4. CR
    Clemens R. Müller

    University of Würzburg, Germany

    8 publications · 1.9K citations

    8

    h-index

  5. JO
    Johannes Oldenburg

    University of Bonn, Germany

    7 publications · 1.9K citations

    7

    h-index

1–5 of 1.5K

Institutions

552

  1. University of Wisconsin–Madison

    Madison, United States

    10 h-index

    22 publications

    1.3K citations

  2. Tolworth Hospital

    London, United Kingdom

    10 h-index

    22 publications

    786 citations

  3. University of Würzburg

    Würzburg, Germany

    9 h-index

    28 publications

    8.2K citations

  4. University of Alabama at Birmingham

    Birmingham, United States

    8 h-index

    21 publications

    1.7K citations

  5. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    8 h-index

    25 publications

    1.6K citations

  6. Ministère de l'Agriculture et de la Souveraineté alimentaire

    Paris, France

    7 h-index

    15 publications

    397 citations

  7. University of Florida

    Gainesville, United States

    6 h-index

    10 publications

    1.8K citations

  8. University of Tennessee Health Science Center

    Memphis, United States

    6 h-index

    27 publications

    1.1K citations

1–8 of 552

Venues

  1. Blood

    19 publications · 2.8K citations

    18

    h-index

  2. Thrombosis Research

    19 publications · 746 citations

    14

    h-index

  3. 11

    h-index

  4. Journal of Hygiene

    11 publications · 313 citations

    11

    h-index

  5. PubMed

    Repository · 10 publications · 391 citations

    10

    h-index

1–5