Concepedia
Immunity · 2005 · 223 citations · 35 references
Open access
Life SciencesImmunologyMolecular BiologyInflammationInnate ImmunitySignal TransductionCytokine Receptor SignalingProtein Kinase CascadesProtein PhosphorylationProtein SynthesisTranslational Regulation
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A synthetic inhibitor of the mitogen-activated protein kinase cascade.
David T. Dudley, Long Pang, Stuart J. Decker et al. · Proceedings of the National Academy of Sciences · 1995 · 2.7K citations · Full text
Life Sciences, Biochemistry, Pharmacology +15
SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin‐1
Ana Cuenda, J.B. Rouse, Yair N. Doza et al. · FEBS Letters · 1995 · 2.1K citations
Life Sciences, Molecular Biology, Pharmacology +14
Impaired On/Off Regulation of TNF Biosynthesis in Mice Lacking TNF AU-Rich Elements
Dimitris L. Kontoyiannis, Manolis Pasparakis, Theresa T. Pizarro et al. · Immunity · 1999 · 1.4K citations · Full text
Life Sciences, Immunology, Molecular Biology +12
Mitogen‐activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2
Andrew J. Waskiewicz · The EMBO Journal · 1997 · 945 citations · Full text
Life Sciences, Biochemistry, Molecular Biology +7
TNF-α Induction by LPS Is Regulated Posttranscriptionally via a Tpl2/ERK-Dependent Pathway
Calin Dan Dumitru, Jeffrey D. Ceci, Christos Tsatsanis et al. · Cell · 2000 · 803 citations · Full text
Life Sciences, Immunology, Molecular Biology +9