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TNF-α Induction by LPS Is Regulated Posttranscriptionally via a Tpl2/ERK-Dependent Pathway

Calin Dan Dumitru, Jeffrey D. Ceci, Christos Tsatsanis, Dimitris L. Kontoyiannis, Konstantinos Stamatakis, Jun‐Hsiang Lin, Christos Patriotis, Nancy A. Jenkins, Neal G. Copeland, George Kollias,

Cell · 2000 · 803 citations · 38 references

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38

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in <i>Tlr4</i> Gene

Alexander Poltorak, Xiaolong He, Irina Smirnova et al. · Science · 1998 · 7.6K citations

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A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

Ruslan Medzhitov, Paula Preston‐Hurlburt, Charles A. Janeway · Nature · 1997 · 5.5K citations

, , +13

A reagent for the single-step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples.

Piotr Chomczyński · PubMed · 1993 · 2.8K citations

, , +17

A synthetic inhibitor of the mitogen-activated protein kinase cascade.

David T. Dudley, Long Pang, Stuart J. Decker et al. · Proceedings of the National Academy of Sciences · 1995 · 2.7K citations · Full text

, , +15

Unresponsiveness of MyD88-Deficient Mice to Endotoxin

Taro Kawai, Osamu Adachi, Tomohiko Ogawa et al. · Immunity · 1999 · 2.1K citations · Full text

, , +8