Major SNP (Q141K) Variant of Human ABC Transporter ABCG2 Undergoes Lysosomal and Proteasomal Degradations

Principles that Govern the Folding of Protein Chains

Christian B. Anfinsen · Science · 1973 · 7.1K citations

Life Sciences, Biochemistry, Biophysics +17

A multidrug resistance transporter from human MCF-7 breast cancer cells

L. Austin Doyle, Weidong Yang, Lynne V. Abruzzo et al. · Proceedings of the National Academy of Sciences · 1998 · 2.3K citations

Medicine, Oncology, Pharmacology +16

The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype

Sheng Zhou, John D. Schuetz, Kevin D. Bunting et al. · Nature Medicine · 2001 · 2.3K citations

Life Sciences, Cell Biology, Molecular Biology +7

Molecular cloning of cDNAs which are highly overexpressed in mitoxantrone-resistant cells: demonstration of homology to ABC transport genes.

Keisuke Miyake, Lyn A. Mickley, Thomas Litman et al. · PubMed · 1999 · 822 citations · Full text

Medicine, Molecular Biology, Oncology +14

A human placenta-specific ATP-binding cassette gene (ABCP) on chromosome 4q22 that is involved in multidrug resistance.

R Allikmets, Lynn M. Schriml, Amy Hutchinson et al. · PubMed · 1998 · 800 citations

Life Sciences, Genetics, Molecular Genetics +14