Roles of CYP3A4 and CYP2C19 in methyl hydroxylated and N-oxidized metabolite formation from voriconazole, a new anti-fungal agent, in human liver microsomes

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Crystal Structures of Human Cytochrome P450 3A4 Bound to Metyrapone and Progesterone

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Identification of the Cytochrome P450 Enzymes Involved in the N-Oxidation of Voriconazole

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Medicine, Biochemistry, Pharmacology +17

THE DISPOSITION OF VORICONAZOLE IN MOUSE, RAT, RABBIT, GUINEA PIG, DOG, AND HUMAN

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Medicine, Pharmacokinetics, Pharmacology +13

Drug metabolism by Escherichia coli expressing human cytochromes P450

Asit Parikh, Elizabeth M. J. Gillam, F. Peter Guengerich · Nature Biotechnology · 1997 · 289 citations

Medicine, Biochemistry, Pharmacology +16