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The effect of pH on the aerobic and hypoxic cytotoxicity of SR4233 in HT-29 cells

Skarsgard Ld, Skwarchuk Mw, A Vinczan, Chaplin Dj

British Journal of Cancer · 1993 · 11 citations · 12 references

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Concepts

References

12

Intermittent blood flow in a murine tumor: radiobiological effects.

David J. Chaplin, Peggy L. Olive, Ralph E. Durand · PubMed · 1987 · 438 citations

, , +13

SR-4233: A new bioreductive agent with high selective toxicity for hypoxic mammalian cells

Elaine M. Zeman, Jeremy Brown, Marilyn J. Lemmon et al. · International Journal of Radiation Oncology*Biology*Physics · 1986 · 395 citations

, , +8

Acute hypoxia in tumors: Implications for modifiers of radiation effects

David J. Chaplin, R. E. Durand, Peggy L. Olive · International Journal of Radiation Oncology*Biology*Physics · 1986 · 267 citations

, , +14

Molecular mechanisms for the hypoxiadependent activation of 3-amino-1,2,4-benzotriazine-1, 4-dioxide (SR 4233)

Keith R. Laderoute, Peter Wardman, Andrew M. Rauth · Biochemical Pharmacology · 1988 · 156 citations

, , +12

Metabolism of SR 4233 by Chinese hamster ovary cells: basis of selective hypoxic cytotoxicity.

Martha Baker, Elaine M. Zeman, V.Kate Hirst et al. · PubMed · 1988 · 121 citations

, , +16