Mechanism of action of bradykinin-induced release of prostaglandin E

An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation

Salvador Moncada, Ryszard J. Gryglewski, S Bunting et al. · Nature · 1976 · 3.6K citations

Medicine, Biochemistry, Pharmacology +16

Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides.

Mats Hámberg, Jan Olof Svensson, B Samuelsson · Proceedings of the National Academy of Sciences · 1975 · 3.1K citations · Full text

Medicine, Pharmacology, Biochemical Pharmacology +14

Prostaglandins: Their Disappearance from and Release into the Circulation

S. H. Ferreira, John R. Vane · Nature · 1967 · 899 citations

Life Sciences, Biochemistry, Pharmacology +5

Release of Additional Factors in Anaphylaxis and its Antagonism by Anti-inflammatory Drugs

Priscilla J. Piper, John R. Vane · Nature · 1969 · 887 citations

Life Sciences, Immunology, Pharmacology +14

Antibodies to Bradykinin and Angiotensin: A Use of Carbodiimides in Immunology

Theodore L. Goodfriend, Lawrence Levine, Gerald D. Fasman · Science · 1964 · 815 citations

Pharmacy, Biochemistry, Immunology +6