Effects of PGI2 and PGI analogues on cAMP levels in cultured endothelial and smooth muscle cells derived from bovine arteries

An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation

Salvador Moncada, Ryszard J. Gryglewski, S Bunting et al. · Nature · 1976 · 3.6K citations

Medicine, Biochemistry, Pharmacology +16

A Protein Binding Assay for Adenosine 3′:5′-Cyclic Monophosphate

Alfred G. Gilman · Proceedings of the National Academy of Sciences · 1970 · 3.3K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Differential formation of prostacyclin (PGX or PGI2) by layers of the arterial wall. An explanation for the anti-thrombotic properties of vascular endothelium

Salvador Moncada, A.G. Herman, E.A. Higgs et al. · Thrombosis Research · 1977 · 684 citations

Medicine, Cell Biology, Pharmacology +14

Properties of calf endothelial cells in culture.

Macarak Ej, Howard Bv, Kefalides Na · PubMed · 1977 · 98 citations

Life Sciences, Cell Biology, Cell Physiology +9

The mechanical properties of some binders used in tableting

J. N. C. HEALEY, Michael Rubinstein, V Walters · Journal of Pharmacy and Pharmacology · 1974 · 39 citations

Natural Sciences, Materials Engineering, Materials Science +17