New Carrier Protein(s) of Folic Acid in Human Serum

Abstract

α2-Macroglobulin, a carrier of folic acid activity (FAA), was isolated from fresh human serum by DEAE Sephadex A-50 gel chroma-, tography. The FAA content of the maximum with α2-macroglobulin was 136 pg/mg protein and constituted 42% of the FAA eluated with the totalproteins from the chromatography column. Theresults was corroborated by controlled retesting.