Analytical Chemistry · 2002 · 304 citations · 27 references
EngineeringChemical EngineeringMaterials ScienceMicrofabricationSemiconductor DevicesSensorsAcoustic SensorsChemical SensorsGas SensorsMems SensorsMicroelectromechanical SensorsVolatile Organic CompoundsGas SensingMass SensingMass-sensitive SensorsMicrocantilever DesignMicrofabricated SensorsMicromachined SensorsVolatile Organic Compound DetectionVolatile Organic Compound Sensing
The sensing behavior of polymer-coated resonant cantilevers for mass-sensitive detection of volatile organic compounds was investigated. Industrial complementary metal oxide semiconductor (CMOS) technology combined with subsequent CMOS-compatible micromachining was used to fabricate a single-chip system comprising the transducers and all necessary driving and signal-conditioning circuitry. An analytical model was developed to describe the mass-sensing mechanism of polymer-coated resonant cantilevers. The model was validated by measurements of various gaseous analytes. As an exemplary application, the quantitative analysis of a binary mixture using an array of four cantilevers is described. Experimental results are given for the concentration prediction of a mixture of n-octane and toluene. Finally, it was established that the limit of detection achieved with cantilever sensors is comparable to that of other acoustic wave-based gas sensors.
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Translating Biomolecular Recognition into Nanomechanics
Jürgen Fritz, Marko Baller, H.P. Lang et al. · Science · 2000 · 1.6K citations
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Christoph Hagleitner, Andreas Hierlemann, D. Lange et al. · Nature · 2001 · 614 citations
Engineering, Chemical Engineering, Electrical Engineering +12