Concepedia

Discovery of novel pyrimidine and malonamide derivatives as TGR5 agonists

Eun Ju Park, Young Gil Ahn, Seung‐Hyun Jung, Hyo Jeong Bang, Mi‐Ra Kim, Dong Jin Hong, Jisook Kim, Kwee Hyun Suh, Young Jin Kim, Doran Kim,

Bioorganic & Medicinal Chemistry Letters · 2014 · 12 citations · 12 references

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12

Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation

Mitsuhiro Watanabe, Sander M. Houten, Chikage Mataki et al. · Nature · 2006 · 2.2K citations · Full text

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TGR5-Mediated Bile Acid Sensing Controls Glucose Homeostasis

Charles Thomas, Antimo Gioiello, Lilia G. Noriega et al. · Cell Metabolism · 2009 · 1.8K citations · Full text

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A G Protein-coupled Receptor Responsive to Bile Acids

Yuji Kawamata, Ryo Fujii, Masaki Hosoya et al. · Journal of Biological Chemistry · 2003 · 1.6K citations · Full text

, , +17

Identification of membrane-type receptor for bile acids (M-BAR)

Takaharu Maruyama, Yasuhisa Miyamoto, Takao Nakamura et al. · Biochemical and Biophysical Research Communications · 2002 · 975 citations

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TGR5 Activation Inhibits Atherosclerosis by Reducing Macrophage Inflammation and Lipid Loading

Thijs W.H. Pols, Mitsunori Nomura, Taoufiq Harach et al. · Cell Metabolism · 2011 · 582 citations · Full text

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