Orally active C-6 heteroaryl- and heterocyclyl-substituted imidazo[1,2-a]pyridine acid pump antagonists (APAs)

Inhibition of gastric H+,K+-ATPase and acid secretion by SCH 28080, a substituted pyridyl(1,2a)imidazole.

B. Wallmark, Carin Briving, J. Fryklund et al. · Journal of Biological Chemistry · 1987 · 232 citations · Full text

Medicine, Biochemistry, Pharmacology +13

Antiulcer Agents. 6. Analysis of the in Vitro Biochemical and in Vivo Gastric Antisecretory Activity of Substituted Imidazo[1,2-<i>a</i>]pyridines and Related Analogues Using Comparative Molecular Field Analysis and Hypothetical Active Site Lattice Methodologies

James J. Kaminski, Arthur M. Doweyko · Journal of Medicinal Chemistry · 1997 · 198 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Antiulcer agents. 1. Gastric antisecretory and cytoprotective properties of substituted imidazo[1,2-a]pyridines

James J. Kaminski, James A. Bristol, Chester Puchalski et al. · Journal of Medicinal Chemistry · 1985 · 118 citations

Natural Sciences, Chemistry, Pharmacology +9

A Randomized, Comparative Trial of a Potassium-Competitive Acid Blocker (AZD0865) and Esomeprazole for the Treatment of Patients With Nonerosive Reflux Disease

John Dent, Peter J. Kahrilas, Jan Gunnar Hatlebakk et al. · The American Journal of Gastroenterology · 2008 · 108 citations

Medicine, Clinical Sciences, Pharmacotherapy +17

A Randomized, Comparative Study of Three Doses of AZD0865 and Esomeprazole for Healing of Reflux Esophagitis

Peter J. Kahrilas, John Dent, K. Lauritsen et al. · Clinical Gastroenterology and Hepatology · 2007 · 103 citations

Medicine, Clinical Sciences, Pharmacotherapy +11