Concepedia

Development of new methodology for the synthesis of functionalized α-fluorophosphonates and its practical application to the preparation of phosphopeptide mimetics

Akira Otaka, Etsuko Mitsuyama, Hideaki Watanabe, Hirokazu Tamamura, Nobutaka Fujii

Chemical Communications · 2000 · 35 citations · 15 references

DOI

Concepts

Abstract

New methodology for the synthesis of functionalized α-fluorophosphonates which utilizes organocopper-mediated reduction has been developed and applied to the preparation of a monofluoromethyl-substituted phosphoserine mimetic-containing peptide.

References

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