Mark S. Smyth

Antitumor Activity of PR-171, a Novel Irreversible Inhibitor of the Proteasome

Susan D. Demo, Christopher J. Kirk, Monette Aujay et al. · Cancer Research · 2007 · 675 citations · Full text

Medicine, Oncology, Pharmacology +13

Nonhydrolyzable Phosphotyrosyl Mimetics for the Preparation Of Phosphatase-Resistant SH2 Domain Inhibitors

Terrence R. Burke, Mark S. Smyth, Motoyoshi Nomizu et al. · Biochemistry · 1994 · 196 citations

Life Sciences, Biochemistry, Pharmacology +17

Preparation of fluoro- and hydroxy-4-(phosphonomethyl)-D,L-phenylalanine suitably protected for solid-phase synthesis of peptides containing hydrolytically stable analogs of O-phosphotyrosine

Terrence R. Burke, Mark S. Smyth, Motoyoshi Nomizu et al. · The Journal of Organic Chemistry · 1993 · 162 citations

Natural Sciences, Biochemistry, Chemistry +10

A general method for the preparation of benzylic α,α-difluorophosphonic acids; non-hydrolyzable mimemtics of phosphotyrosine

Mark S. Smyth, Harry Ford, Terrence R. Burke · Tetrahedron Letters · 1992 · 129 citations

Natural Sciences, Biochemistry, Chemistry +6

Why Is Phosphonodifluoromethyl Phenylalanine a More Potent Inhibitory Moiety Than Phosphonomethyl Phenylalanine Toward Protein-Tyrosine Phosphatases

L. Chen, Li Wu, Akihisa Otaka et al. · Biochemical and Biophysical Research Communications · 1995 · 111 citations

Life Sciences, Medicinal Chemistry, Pharmacology +11