Hirokazu Tamamura

A Small Molecule CXCR4 Inhibitor that Blocks T Cell Line–tropic HIV-1 Infection

Tsutomu Murakami, Toshihiro Nakajima, Yoshio Koyanagi et al. · The Journal of Experimental Medicine · 1997 · 399 citations · Full text

Life Sciences, Immunology, Infectious Diseases +16

A Low-Molecular-Weight Inhibitor against the Chemokine Receptor CXCR4: A Strong Anti-HIV Peptide T140

Hirokazu Tamamura, Younong Xu, Toshio Hattori et al. · Biochemical and Biophysical Research Communications · 1998 · 305 citations

Medicine, Medicinal Chemistry, Pharmacology +14

Small peptide inhibitors of the CXCR4 chemokine receptor (CD184) antagonize the activation, migration, and antiapoptotic responses of CXCL12 in chronic lymphocytic leukemia B cells

Meike Burger, Tanja Nicole Hartmann, Myriam Krome et al. · Blood · 2005 · 291 citations

Medicine, Oncology, Pharmacology +17

Remodeling of gp41-C34 Peptide Leads to Highly Effective Inhibitors of the Fusion of HIV-1 with Target Cells We thank Dr. Terrence R. Burke, Jr., NCI, NIH, Frederick, MD 21702-1201, for proofreading the manuscript and providing useful comments. This research was supported in part by a Grant-in-Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology, Japan, the Japan Society for the Promotion of Science, and the Japan Health Science Foundation.

Akira Otaka, Miki Nakamura, Daisuke Nameki et al. · Angewandte Chemie International Edition · 2002 · 163 citations

Life Sciences, Biochemistry, Molecular Biology +14

Identification of a CXCR4 antagonist, a T140 analog, as an anti‐rheumatoid arthritis agent

Hirokazu Tamamura, Miho Fujisawa, Kenichi Hiramatsu et al. · FEBS Letters · 2004 · 137 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17