Concepedia

BRAF mutations characterize colon but not gastric cancer with mismatch repair deficiency

Carla Oliveíra, Mafalda Pinto, Alex Duval, Caroline Brennetot, Enric Domingo, Manel Armengol, Hiroyuki Yamamoto, Richard Hamelin, Raquel Seruca, Simó Schwartz

Oncogene · 2003 · 145 citations · 5 references

Concepts

MedicineMolecular GeneticsOncologyCancer GeneticsGastrointestinal OncologyMolecular OncologyColonic DiseasesColorectal CancerGastric CancerGastrointestinal PathologyMismatch RepairOncogene MutationsBraf V600 MutationsBraf V600e MutationDna Mismatch Repair DeficiencyGastric Cancer GeneticsMismatch Repair DefectsMismatch Repair Gene Mutations

References

5

Mutations of the BRAF gene in human cancer

Helen Davies, Graham R. Bignell, Charles Cox et al. · Nature · 2002 · 10.7K citations

Medicine, Genetics, Molecular Genetics +12

Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

Yurij Ionov, Miguel A. Peinado, Sergei Malkhosyan et al. · Nature · 1993 · 2.7K citations

Medicine, Genetics, Molecular Genetics +17

RAF/RAS oncogenes and mismatch-repair status

Harith Rajagopalan, Alberto Bardelli, Christoph Lengauer et al. · Nature · 2002 · 1.2K citations

Medicine, Genetics, Molecular Biology +14

Gastric cancers of the microsatellite mutator phenotype display characteristic genetic and clinical features☆, ☆☆

Hiroyuki Yamamoto, J Pérez-Piteira, Teruhiko Yoshida et al. · Gastroenterology · 1999 · 188 citations · Full text

Medicine, Genetics, Oncology +16

Extensive characterization of genetic alterations in a series of human colorectal cancer cell lines

Jacqueline Gayet, Xiaoping Zhou, Alex Duval et al. · Oncogene · 2001 · 180 citations

Medicine, Genetics, Oncology +12