Concepedia

A New Route to Spirooxindoles

Stephen T. Hilton, Tim C. T. Ho, Goran Pljevaljčić, Keith Jones

Organic Letters · 2000 · 184 citations · 17 references

DOI

Abstract

[reaction: see text]Reaction of indole amides 5 with tributylstannane gave spiroindolenines 9 which are readily converted into spiropyrrolidinyloxindoles. This tricyclic system is found in a number of interesting natural products.

References

17

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Novel Mammalian Cell Cycle Inhibitors, Tryprostatins A, B and Other Diketopiperazines Produced by Aspergillus fumigatus. I. Taxonomy, Fermentation, Isolation and Biological Properties.

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Dennis P. Curran, Shen Wang · Journal of the American Chemical Society · 1993 · 192 citations

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