Concepedia

Human Small Intestinal Epithelial Cells Differentiated from Adult Intestinal Stem Cells as a Novel System for Predicting Oral Drug Absorption in Humans

Toru Takenaka, Naomoto Harada, Jiro Kuze, Masato Chiba, Takahiro Iwao, Tamihide Matsunaga

Drug Metabolism and Disposition · 2014 · 81 citations · 42 references

DOI

Concepts

References

42

Characterization of the Human Colon Carcinoma Cell Line (Caco-2) as a Model System for Intestinal Epithelial Permeability

Ismael J. Hidalgo, Thomas J. Raub, Ronald T. Borchardt · Gastroenterology · 1989 · 2.2K citations

, , +14

Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro

Jason R. Spence, Christopher N. Mayhew, Scott A. Rankin et al. · Nature · 2010 · 1.9K citations · Full text

, , +16

Characterization of the human colon carcinoma cell line (Caco-2) as a model system for intestinal epithelial permeability

Ismael J. Hidalgo, Thomas J. Raub, Ronald T. Borchardt · Gastroenterology · 1989 · 1.1K citations

, , +14

MDCK (Madin-Darby Canine Kidney) Cells: A Tool for Membrane Permeability Screening

Jennifer D. Irvine, Lori H. Takahashi, Karen Lockhart et al. · Journal of Pharmaceutical Sciences · 1999 · 976 citations

, , +13

Physiologically based pharmacokinetic modelling 2: Predicting the tissue distribution of acids, very weak bases, neutrals and zwitterions

Trudy Rodgers, Malcolm Rowland · Journal of Pharmaceutical Sciences · 2006 · 940 citations

, , +11