Takahiro Iwao

Generation of Intestinal Organoids Suitable for Pharmacokinetic Studies from Human Induced Pluripotent Stem Cells

Daichi Onozato, Misaki Yamashita, Anna Nakanishi et al. · Drug Metabolism and Disposition · 2018 · 95 citations · Full text

Life Sciences, Cell Biology, Pharmacology +16

Human Small Intestinal Epithelial Cells Differentiated from Adult Intestinal Stem Cells as a Novel System for Predicting Oral Drug Absorption in Humans

Toru Takenaka, Naomoto Harada, Jiro Kuze et al. · Drug Metabolism and Disposition · 2014 · 81 citations

Life Sciences, Cell Biology, Pharmacology +14

Differentiation of Human Induced Pluripotent Stem Cells into Functional Enterocyte-like Cells Using a Simple Method

Takahiro Iwao, Masashi Toyota, Yoshitaka Miyagawa et al. · Drug Metabolism and Pharmacokinetics · 2013 · 63 citations

Life Sciences, Biotechnology, Cell Biology +8

An Efficient Method for Differentiation of Human Induced Pluripotent Stem Cells into Hepatocyte-like Cells Retaining Drug Metabolizing Activity

Yuki Kondo, Takahiro Iwao, Katsunori Nakamura et al. · Drug Metabolism and Pharmacokinetics · 2013 · 58 citations · Full text

Life Sciences, Biotechnology, Cell Differentiation +12

Application of a Human Intestinal Epithelial Cell Monolayer to the Prediction of Oral Drug Absorption in Humans as a Superior Alternative to the Caco-2 Cell Monolayer

Toru Takenaka, Naomoto Harada, Jiro Kuze et al. · Journal of Pharmaceutical Sciences · 2016 · 57 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +16