PU.1 and Spi-B Are Required for Normal B Cell Receptor–Mediated Signal Transduction

A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin μ chain gene

Daisuke Kitamura, Jürgen Roes, Ralf Kühn et al. · Nature · 1991 · 1.8K citations

Life Sciences, Genetics, Immunology +12

Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow.

Richard R. Hardy, Condie E. Carmack, Susan A. Shinton et al. · The Journal of Experimental Medicine · 1991 · 1.6K citations · Full text

Life Sciences, Cell Biology, Immunology +17

Requirement of Transcription Factor PU.1 in the Development of Multiple Hematopoietic Lineages

Edward W. Scott, M. Celeste Simon, John Anastasi et al. · Science · 1994 · 1.5K citations

Life Sciences, Developmental Biology, Genetics +17

Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities.

Scott R. McKercher, Bruce E. Torbett, Kenton L. Anderson et al. · The EMBO Journal · 1996 · 1.1K citations · Full text

Life Sciences, Genetics, Molecular Genetics +10

In Vivo Ablation of Surface Immunoglobulin on Mature B Cells by Inducible Gene Targeting Results in Rapid Cell Death

Kong‐Peng Lam, Ralf Kühn, Klaus Rajewsky · Cell · 1997 · 1.1K citations · Full text

Life Sciences, Immunology, Molecular Biology +17