Concepedia

Relationship between the inhibitory potencies of thiorphan and retrothiorphan enantiomers on thermolysin and neutral endopeptidase 24.11 and their interactions with the thermolysin active site by computer modelling

T. Benchetrit, M C Fournié-Zaluski, B.P. Roques

Biochemical and Biophysical Research Communications · 1987 · 47 citations · 17 references

DOI

Concepts

References

17

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

, , +14

Design of Specific Inhibitors of Angiotensin-Converting Enzyme: New Class of Orally Active Antihypertensive Agents

Miguel A. Ondetti, Bernard Rubin, David W. Cushman · Science · 1977 · 1.9K citations

, , +16

The enkephalinase inhibitor thiorphan shows antinociceptive activity in mice

B P Roques, M C Fournié-Zaluski, E. Soroca et al. · Nature · 1980 · 707 citations

, , +10

High-affinity enkephalin-degrading peptidase in brain is increased after morphine

Bernard Malfroy, Jean-Paul Swerts, Anne Guyon et al. · Nature · 1978 · 650 citations

, , +12

The purification and specificity of a neutral endopeptidase from rabbit kidney brush border

M. A. Kerr, A J Kenny · Biochemical Journal · 1974 · 462 citations · Full text

, , +17