Concepedia

Expression of Lgr5 in human colorectal carcinogenesis and its potential correlation with β-catenin

Xiangshan Fan, Hongyan Wu, Huiping Yu, Qiang Zhou, Yifen Zhang, Qin Huang

International Journal of Colorectal Disease · 2010 · 80 citations · 18 references

DOI

Concepts

References

18

Identification of stem cells in small intestine and colon by marker gene Lgr5

Nick Barker, Johan H. van Es, Jeroen Kuipers et al. · Nature · 2007 · 5.7K citations

, , +16

Crypt stem cells as the cells-of-origin of intestinal cancer

Nick Barker, Rachel A. Ridgway, Johan H. van Es et al. · Nature · 2008 · 2.2K citations

, , +14

Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4

Vladimír Kořínek, Nick Barker, Petra Moerer et al. · Nature Genetics · 1998 · 1.6K citations

, , +14

Notch/γ-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells

Johan H. van Es, Mariëlle van Gijn, Orbicia Riccio et al. · Nature · 2005 · 1.5K citations · Full text

, , +15

BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt–β-catenin signaling

Xi He, Jiwang Zhang, Wei-Gang Tong et al. · Nature Genetics · 2004 · 1.1K citations · Full text

, , +14