Involvement of heme oxygenase-1 induction via Nrf2/ARE activation in protection against H2O2-induced PC12 cell death by a metabolite of sesamin contained in sesame seeds

An Nrf2/Small Maf Heterodimer Mediates the Induction of Phase II Detoxifying Enzyme Genes through Antioxidant Response Elements

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Alzheimer's Disease and Senile Dementia: Loss of Neurons in the Basal Forebrain

PJ Whitehouse, DL Price, R. G. Struble et al. · Science · 1982 · 3.6K citations

Life Sciences, Neurobiology, Neuroscience +17

Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants

Albena T. Dinkova‐Kostova, W. David Holtzclaw, Robert N. Cole et al. · Proceedings of the National Academy of Sciences · 2002 · 1.9K citations · Full text

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Amelioration of cholinergic neuron atrophy and spatial memory impairment in aged rats by nerve growth factor

Walter Fischer, Klas Wictorin, Anders Björklund et al. · Nature · 1987 · 1K citations

Medicine, Neurobiology, Neuroscience +16

Curcumin activates the haem oxygenase-1 gene via regulation of Nrf2 and the antioxidant-responsive element

Elisabeth Abidemi Balogun, Martha Hoque, Pengfei Gong et al. · Biochemical Journal · 2003 · 1K citations · Full text

Life Sciences, Biochemistry, Pharmacology +17