Concepedia

Identification of Sox9-Dependent Acinar-to-Ductal Reprogramming as the Principal Mechanism for Initiation of Pancreatic Ductal Adenocarcinoma

Janel L. Kopp, Guido von Figura, Erin Mayes, Fenfen Liu, Claire L. Dubois, John P. Morris, Fong Cheng Pan, Haruhiko Akiyama, Christopher V.E. Wright, Kristin C. Jensen,

Cancer Cell · 2012 · 692 citations · 55 references

DOI

Concepts

References

55

Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice

Sunil R. Hingorani, Lifu Wang, Asha S. Multani et al. · Cancer Cell · 2005 · 2.6K citations · Full text

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Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse

Sunil R. Hingorani, Emanuel F. Petricoin, Anirban Maitra et al. · Cancer Cell · 2003 · 2.5K citations · Full text

, , +12

Pancreatitis and the Risk of Pancreatic Cancer

Albert B. Lowenfels, Patrick Maisonneuve, Giorgio Cavallini et al. · New England Journal of Medicine · 1993 · 1.7K citations · Full text

, , +17

Chronic Pancreatitis Is Essential for Induction of Pancreatic Ductal Adenocarcinoma by K-Ras Oncogenes in Adult Mice

Carmen Guerra, Alberto J. Schuhmacher, Marta Cañamero et al. · Cancer Cell · 2007 · 1.2K citations · Full text

, , +9

Activated Kras and <i>Ink4a/Arf</i> deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma

Andrew J. Aguirre, Nabeel Bardeesy, Manisha Sinha et al. · Genes & Development · 2003 · 1K citations · Full text

, , +15