Claire L. Dubois

Identification of Sox9-Dependent Acinar-to-Ductal Reprogramming as the Principal Mechanism for Initiation of Pancreatic Ductal Adenocarcinoma

Janel L. Kopp, Guido von Figura, Erin Mayes et al. · Cancer Cell · 2012 · 679 citations

Signal Transduction, Pancreatic Cancer, Pathology +9

Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas

Janel L. Kopp, Claire L. Dubois, Ashleigh E. Schaffer et al. · Development · 2011 · 467 citations · Full text

Pdl-induced Ngn3, Organ Development, Sox9+ Ductal Cells +21

A Notch-dependent molecular circuitry initiates pancreatic endocrine and ductal cell differentiation

Hung-Ping Shih, Janel L. Kopp, Manbir Sandhu et al. · Development · 2012 · 228 citations · Full text

Cell Differentiation, Pancreatic Endocrine, Cellular Physiology +21

Cell of origin affects tumour development and phenotype in pancreatic ductal adenocarcinoma

Alex Y.L. Lee, Claire L. Dubois, Karnjit Sarai et al. · Gut · 2018 · 135 citations · Full text

A dosage-dependent requirement for Sox9 in pancreatic endocrine cell formation

Philip A. Seymour, Kristine Freude, Claire L. Dubois et al. · Developmental Biology · 2008 · 123 citations · Full text

Pancreatic Cancer, Immunology, Dosage-dependent Requirement +5