Concepedia

Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases

Min Zhuang, Matthew F. Calabrese, Jiang Liu, M. Brett Waddell, Amanda Nourse, Michal Hammel, Darcie J. Miller, Helen Walden, David M. Duda, Steven N. Seyedin,

Molecular Cell · 2009 · 489 citations · 53 references

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53

Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

Ken Itoh, Nobunao Wakabayashi, Yasutake Katoh et al. · Genes & Development · 1999 · 3.6K citations · Full text

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Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb

Jin Jiang, Gary Struhl · Nature · 1998 · 1.7K citations

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Structure of the Cul1–Rbx1–Skp1–F boxSkp2 SCF ubiquitin ligase complex

Ning Zheng, Brenda A. Schulman, Langzhou Song et al. · Nature · 2002 · 1.5K citations

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Distinct Cysteine Residues in Keap1 Are Required for Keap1-Dependent Ubiquitination of Nrf2 and for Stabilization of Nrf2 by Chemopreventive Agents and Oxidative Stress

Donna D. Zhang, Mark Hannink · Molecular and Cellular Biology · 2003 · 1.4K citations · Full text

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SKP1 Connects Cell Cycle Regulators to the Ubiquitin Proteolysis Machinery through a Novel Motif, the F-Box

Chang Bai, Partha Sen, Kay Hofmann et al. · Cell · 1996 · 1.4K citations · Full text

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