Concepedia

The CDK4–pRB–E2F1 pathway controls insulin secretion

Jean‐Sébastien Annicotte, Émilie Blanchet, Carine Chavey, Irena Iankova, Safia Costes, Saïd Assou, Jacques Teyssier, Stéphane Dalle, Claude Sardet, Lluís Fajas

Nature Cell Biology · 2009 · 127 citations · 25 references

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25

Retinoblastoma protein recruits histone deacetylase to repress transcription

Alexander Brehm, Eric A. Miska, Dennis J. McCance et al. · Nature · 1998 · 1.2K citations

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Tissue-Specific Knockout of the Insulin Receptor in Pancreatic β Cells Creates an Insulin Secretory Defect Similar to that in Type 2 Diabetes

Rohit Kulkarni, Jens C. Brüning, Jonathon N. Winnay et al. · Cell · 1999 · 1.2K citations · Full text

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p16INK4a induces an age-dependent decline in islet regenerative potential

Janakiraman Krishnamurthy, Matthew R. Ramsey, Keith L. Ligon et al. · Nature · 2006 · 997 citations

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β cell replication is the primary mechanism for maintaining postnatal β cell mass

Senta Georgia, Anil Bhushan · Journal of Clinical Investigation · 2004 · 493 citations · Full text

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Cyclins D2 and D1 Are Essential for Postnatal Pancreatic β-Cell Growth

Jake A. Kushner, Maria A. Ciemerych, Ewa Sicińska et al. · Molecular and Cellular Biology · 2005 · 330 citations · Full text

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