Concepedia

Splicing regulates NAD metabolite binding to histone macroH2A

Georg Kustatscher, Michael Hothorn, Céline Pugieux, Klaus Scheffzek, Andreas G. Ladurner

Nature Structural & Molecular Biology · 2005 · 294 citations · 14 references

DOI

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14

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

Shin‐ichiro Imai, Christopher M. Armstrong, Matt Kaeberlein et al. · Nature · 2000 · 3.5K citations

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The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases

Joseph W. Landry, Ann Sutton, Stefan T. Tafrov et al. · Proceedings of the National Academy of Sciences · 2000 · 966 citations

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Human SirT1 Interacts with Histone H1 and Promotes Formation of Facultative Heterochromatin

Alejandro Vaquero, Michael Scher, Donghoon Lee et al. · Molecular Cell · 2004 · 917 citations · Full text

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A phylogenetically conserved NAD <sup>+</sup> -dependent protein deacetylase activity in the Sir2 protein family

Jeffrey S. Smith, Carrie Baker Brachmann, Ivana Celic et al. · Proceedings of the National Academy of Sciences · 2000 · 722 citations

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Formation of MacroH2A-Containing Senescence-Associated Heterochromatin Foci and Senescence Driven by ASF1a and HIRA

Rugang Zhang, Maxim Poustovoitov, Xiaofen Ye et al. · Developmental Cell · 2005 · 673 citations · Full text

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