Sequence specific alkylation of DNA by hairpin pyrrole–imidazole polyamide conjugates

Disruption of IRS-2 causes type 2 diabetes in mice

Dominic J. Withers, Julio Sanchez Gutierrez, Heather Towery et al. · Nature · 1998 · 1.8K citations

Life Sciences, Endocrinology, Molecular Biology +12

Autoradiography using storage phosphor technology

Richard F. Johnston, Siobhan C. Pickett, David Barker · Electrophoresis · 1990 · 526 citations

Engineering, Biomedical Engineering, Biomedical Imaging +9

Recognition of the four Watson–Crick base pairs in the DNA minor groove by synthetic ligands

S.W. White, Jason W. Szewczyk, James M. Turner et al. · Nature · 1998 · 499 citations

Life Sciences, Biology, Molecular Biology +12

Regulation of gene expression by small molecules

Joel Gottesfeld, Laura Neely, John W. Trauger et al. · Nature · 1997 · 471 citations

Life Sciences, Biochemistry, Molecular Biology +13

Recognition of DNA by designed ligands at subnanomolar concentrations

John W. Trauger, Eldon E. Baird, Peter B. Dervan · Nature · 1996 · 397 citations

Pharmacy, Chemical Biology, Molecular Biology +12