Joel Gottesfeld

Dynamic Changes in the Copy Number of Pluripotency and Cell Proliferation Genes in Human ESCs and iPSCs during Reprogramming and Time in Culture

Louise C. Laurent, Igor Ulitsky, Ileana Slavin et al. · Cell stem cell · 2011 · 894 citations · Full text

Life Sciences, Cell Biology, Genetics +17

Regulation of gene expression by small molecules

Joel Gottesfeld, Laura Neely, John W. Trauger et al. · Nature · 1997 · 471 citations

Life Sciences, Biochemistry, Molecular Biology +13

Histone deacetylase inhibitors reverse gene silencing in Friedreich's ataxia

David Herman, Kai Jenssen, Ryan Burnett et al. · Nature Chemical Biology · 2006 · 435 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +14

The HDAC inhibitor 4b ameliorates the disease phenotype and transcriptional abnormalities in Huntington's disease transgenic mice

Elizabeth A. Thomas, Giovanni Coppola, Paula Desplats et al. · Proceedings of the National Academy of Sciences · 2008 · 290 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis

Darren M. Hutt, David Herman, Ana P. C. Rodrigues et al. · Nature Chemical Biology · 2009 · 250 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15