Concepedia

A cell-based immunocytochemical assay for monitoring kinase signaling pathways and drug efficacy

Huaxian Chen, Joy L. Kovar, Sean E. Sissons, Karen L. Cox, William F. Matter, Fred Chadwell, Peng Luan, Chris J. Vlahos, Amy Schutz‐Geschwender, D. Michael Olive

Analytical Biochemistry · 2004 · 86 citations · 8 references

DOI

Concepts

References

8

A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002).

Chris J. Vlahos, William F. Matter, K. Y. Hui et al. · Journal of Biological Chemistry · 1994 · 3.3K citations · Full text

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Integrated Genomic and Proteomic Analyses of a Systematically Perturbed Metabolic Network

Trey Ideker, Vésteinn Thórsson, Jeffrey A. Ranish et al. · Science · 2001 · 2.1K citations

, , +15

Specific, irreversible inactivation of the epidermal growth factor receptor and erbB2, by a new class of tyrosine kinase inhibitor

David W. Fry, Alexander J. Bridges, William A. Denny et al. · Proceedings of the National Academy of Sciences · 1998 · 418 citations

, , +17

Cancer and genomics

P. Andrew Futreal, Arek Kasprzyk, Ewan Birney et al. · Nature · 2001 · 147 citations · Full text

Overcoming Compound Interference in Fluorescence Polarization-Based Kinase Assays Using Far-Red Tracers

Kevin L. Vedvik, Hildegard C. Eliason, Randy Hoffman et al. · Assay and Drug Development Technologies · 2004 · 54 citations

, , +13