Concepedia
The EMBO Journal · 2001 · 199 citations · 34 references
Open access
Transcriptional RegulationSignal TransductionEngineeringRna PolymeraseRna BiologyGene RegulationMolecular BiologyGene TranscriptionSystems BiologyMedicineGene ExpressionRna ProcessingTranscription Regulation
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Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
Shin‐ichiro Imai, Christopher M. Armstrong, Matt Kaeberlein et al. · Nature · 2000 · 3.5K citations
Histone Modifications, Chromatin, Transcriptional Regulation +12
Activation of p53 Sequence-Specific DNA Binding by Acetylation of the p53 C-Terminal Domain
Wei Gu, R G Roeder · Cell · 1997 · 2.5K citations · Full text
P53 C-terminal Domain, Molecular Biology, Molecular Basis +4
A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A
Xiang‐Jiao Yang, Vasily Ogryzko, Jun‐ichi Nishikawa et al. · Nature · 1996 · 1.5K citations
P300/cbp-associated Factor, Oncogenic Agent, Pathology +8
DNA damage activates p53 through a phosphorylation–acetylation cascade
Kazuyasu Sakaguchi, Julio E. Herrera, Shinichi Saito et al. · Genes & Development · 1998 · 1.2K citations · Full text
Chromatin, Genome Instability, Transcriptional Regulation +11
A direct link between core histone acetylation and transcriptionally active chromatin.
Tim R. Hebbes, Alan W. Thorne, Colyn Crane‐Robinson · The EMBO Journal · 1988 · 914 citations · Full text
Histone Modifications, Epigenetic Change, Molecular Biology +18