Concepedia

Generation of tumor-targeted human T lymphocytes from induced pluripotent stem cells for cancer therapy

Maria Themeli, Christopher C. Kloss, Giovanni Ciriello, V D Fedorov, Fabiana Perna, Mithat Gönen, Michel Sadelain

Nature Biotechnology · 2013 · 468 citations · 31 references

DOIFull text

Open access

Concepts

References

31

Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors

Kazutoshi Takahashi, Koji Tanabe, Mari Ohnuki et al. · Cell · 2007 · 20.2K citations

, , +12

Proportional hazards tests and diagnostics based on weighted residuals

Patricia M. Grambsch, Terry M. Therneau · Biometrika · 1994 · 5.6K citations

, , +16

T Cells with Chimeric Antigen Receptors Have Potent Antitumor Effects and Can Establish Memory in Patients with Advanced Leukemia

Michael Kalos, Bruce L. Levine, David L. Porter et al. · Science Translational Medicine · 2011 · 2.4K citations · Full text

, , +17

CD19-Targeted T Cells Rapidly Induce Molecular Remissions in Adults with Chemotherapy-Refractory Acute Lymphoblastic Leukemia

Renier J. Brentjens, Marco L. Davila, Isabelle Rivière et al. · Science Translational Medicine · 2013 · 2.1K citations · Full text

, , +13

B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor–transduced T cells

James N. Kochenderfer, Mark E. Dudley, Steven A. Feldman et al. · Blood · 2011 · 1.4K citations

, , +17