Concepedia

Optimal antidiarrhea treatment for antitumor agent irinotecan hydrochloride (CPT-11)-induced delayed diarrhea

Kiyoshi Takasuna, Toshihiko Hagiwara, Kyohei Watanabe, S. Onose, Susumu Yoshida, Eiji Kumazawa, Eiichi Nagai, Tetsuya Kamataki

Cancer Chemotherapy and Pharmacology · 2006 · 79 citations · 60 references

DOI

Concepts

References

60

Irinotecan plus Cisplatin Compared with Etoposide plus Cisplatin for Extensive Small-Cell Lung Cancer

Kazumasa Noda, Yutaka Nishiwaki, Masaaki Kawahara et al. · New England Journal of Medicine · 2002 · 1.4K citations · Full text

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A Pooled Analysis of Adjuvant Chemotherapy for Resected Colon Cancer in Elderly Patients

Daniel J. Sargent, Richard M. Goldberg, Stacy D. Jacobson et al. · New England Journal of Medicine · 2001 · 994 citations · Full text

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Intracellular roles of SN-38, a metabolite of the camptothecin derivative CPT-11, in the antitumor effect of CPT-11.

Yasuyoshi Kawato, Masashi Aonuma, Yasuhide Hirota et al. · PubMed · 1991 · 874 citations

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Polymorphisms of UDP-glucuronosyltransferase gene and irinotecan toxicity: a pharmacogenetic analysis.

Yukio Ando, Hideo Saka, Maki Ando et al. · PubMed · 2000 · 788 citations

, , +15

Metabolic fate of irinotecan in humans: correlation of glucuronidation with diarrhea.

E Gupta, Timothy M. Lestingi, Rosemarie Mick et al. · PubMed · 1994 · 506 citations

, , +14