Concepedia

Human T Regulatory Cells Can Use the Perforin Pathway to Cause Autologous Target Cell Death

William J. Grossman, James Verbsky, Winfried Barchet, Marco Colonna, John Atkinson, Timothy J. Ley

Immunity · 2004 · 999 citations · 45 references

DOI

Concepts

References

45

Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha.

Federica Sallusto, Antonio Lanzavecchia · The Journal of Experimental Medicine · 1994 · 5.2K citations · Full text

, , +17

CD4+CD25high Regulatory Cells in Human Peripheral Blood

Clare Baecher‐Allan, Julia A. Brown, Gordon J. Freeman et al. · The Journal of Immunology · 2001 · 1.8K citations · Full text

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Cell Contact–Dependent Immunosuppression by Cd4+Cd25+Regulatory T Cells Is Mediated by Cell Surface–Bound Transforming Growth Factor β

Kazuhiko Nakamura, Atsushi Kitani, Warren Strober · The Journal of Experimental Medicine · 2001 · 1.6K citations · Full text

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Identification and Functional Characterization of Human Cd4+Cd25+ T Cells with Regulatory Properties Isolated from Peripheral Blood

Helmut Jonuleit, Edgar Schmitt, Michael Stassen et al. · The Journal of Experimental Medicine · 2001 · 1.2K citations · Full text

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Perforin Gene Defects in Familial Hemophagocytic Lymphohistiocytosis

Susan E. Stepp, Rémi Dufourcq-Lagelouse, Françoise Le Deist et al. · Science · 1999 · 1.2K citations

, , +15