Winfried Barchet

Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus

Leonid Gitlin, Winfried Barchet, Susan Gilfillan et al. · Proceedings of the National Academy of Sciences · 2006 · 1.2K citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3

Thirumala‐Devi Kanneganti, Nesrin Özören, Mathilde Body–Malapel et al. · Nature · 2006 · 1.1K citations

Life Sciences, Microbiology, Molecular Biology +14

Cyclic [G(2′,5′)pA(3′,5′)p] Is the Metazoan Second Messenger Produced by DNA-Activated Cyclic GMP-AMP Synthase

Pu Gao, Manuel Ascano, Yang Wu et al. · Cell · 2013 · 1.1K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +11

Human T Regulatory Cells Can Use the Perforin Pathway to Cause Autologous Target Cell Death

William J. Grossman, James Verbsky, Winfried Barchet et al. · Immunity · 2004 · 999 citations

Life Sciences, Cell Biology, Immunology +15

Ribose 2′-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5

Roland Züst, Luisa Cervantes‐Barragán, Matthias Habjan et al. · Nature Immunology · 2011 · 802 citations · Full text

Life Sciences, Biology, Molecular Biology +15