A bacterial glycosidase enables mannose-6-phosphate modification and improved cellular uptake of yeast-produced recombinant human lysosomal enzymes

Petra Tiels, E.V. Baranova, Kathleen Piens, Charlotte De Visscher, Gwenda Pynaert, Wim Nerinckx, Jan Stout, Franck Fudalej, Paco Hulpiau, Simon Tännler,

Nature Biotechnology · 2012 · 110 citations · 33 references

Concepts

References

33