Genetic disruption of Abl nuclear import reduces renal apoptosis in a mouse model of cisplatin-induced nephrotoxicity

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

Jamil Momand, Gerard P. Zambetti, David C. Olson et al. · Cell · 1992 · 3.1K citations

Oncogenic Agent, Medicine, Molecular Biology +9

Tumor spectrum analysis in p53-mutant mice

Tyler Jacks, Lee Ann Remington, Bart O. Williams et al. · Current Biology · 1994 · 2.1K citations

Tumor Biology, Tumor Heterogeneity, Tumor Spectrum Analysis +3

Direct Activation of Bax by p53 Mediates Mitochondrial Membrane Permeabilization and Apoptosis

Jerry E. Chipuk, Tomomi Kuwana, Lisa Bouchier‐Hayes et al. · Science · 2004 · 2K citations

Apoptosis, Molecular Biology, Cell Death +19

p53 Has a Direct Apoptogenic Role at the Mitochondria

Motohiro Mihara, Susan Erster, Alexander Zaika et al. · Molecular Cell · 2003 · 1.8K citations · Full text

Mitochondrial Function, Cell Death, Medicine +2

Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene

Victor L. J. Tybulewicz, C. Crawford, Peter K. Jackson et al. · Cell · 1991 · 1.3K citations

Knockout Mouse, Developmental Biology, Lymphocyte Development +9