Concepedia

The EP4 receptor antagonist, L-161,982, blocks prostaglandin E2-induced signal transduction and cell proliferation in HCA-7 colon cancer cells

Durga Cherukuri, Xi Chen, Anne‐Christine Goulet, Robert N. Young, Yoonseok Han, Ronald L. Heimark, John W. Regan, Emmanuelle J. Meuillet, Michael R. Nelson

Experimental Cell Research · 2007 · 78 citations · 43 references

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43

New Colorimetric Cytotoxicity Assay for Anticancer-Drug Screening

Philip Skehan, Ritsa Storeng, Dominic A. Scudiero et al. · JNCI Journal of the National Cancer Institute · 1990 · 9.8K citations

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Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas

Charles E. Eberhart, R J Coffey, Radhika Aramandla et al. · Gastroenterology · 1994 · 2.5K citations · Full text

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Suppression of Intestinal Polyposis in ApcΔ716 Knockout Mice by Inhibition of Cyclooxygenase 2 (COX-2)

Masanobu Oshima, Joseph Dinchuk, Stacia Kargman et al. · Cell · 1996 · 2.4K citations · Full text

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Prostaglandin E <sub>2</sub> Promotes Colon Cancer Cell Growth Through a G <sub>s</sub> -Axin-ß-Catenin Signaling Axis

Maria Domenica Castellone, Hidemi Teramoto, Bart O. Williams et al. · Science · 2005 · 884 citations

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Prostaglandin E2 transactivates EGF receptor: A novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy

Rama Pai, Brian Soreghan, Imre Szabó et al. · Nature Medicine · 2002 · 833 citations

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