Concepedia

Mechanism-Based Pharmacokinetic–Pharmacodynamic Modeling—A New Classification of Biomarkers

Meindert Danhof, Gunnar Alván, Svein G. Dahl, J. Kuhlmann, Gilles Paintaud

Pharmaceutical Research · 2005 · 163 citations · 36 references

DOI

Concepts

References

36

Simultaneous modeling of pharmacokinetics and pharmacodynamics: Application to <i>d</i>‐tubocurarine

Lewis B. Sheiner, Donald R. Stanski, Samuel Vožeh et al. · Clinical Pharmacology & Therapeutics · 1979 · 1.1K citations

, , +17

Operational models of pharmacological agonism

J.W. Black, P. Leff · Proceedings of the Royal Society of London. Series B, Biological sciences · 1983 · 1.1K citations

, , +16

Comparison of four basic models of indirect pharmacodynamic responses

Natalie Dayneka, Varun Garg, William J. Jusko · Journal of Pharmacokinetics and Biopharmaceutics · 1993 · 811 citations

, , +14

Central D2-dopamine receptor occupancy in relation to antipsychotic drug effects: A double-blind PET study of schizophrenic patients

Anna Nordström, Lars Farde, Frits‐Axel Wiesel et al. · Biological Psychiatry · 1993 · 530 citations

, , +17

EEG Quantitation of Narcotic Effect

James C. Scott, Katherine V. Ponganis, Donald R. Stanski · Anesthesiology · 1985 · 501 citations · Full text

, , +8