Arginine Methylation Facilitates the Recruitment of TOP3B to Chromatin to Prevent R Loop Accumulation

Supercoiling of the DNA template during transcription.

Leroy F. Liu, J C Wang · Proceedings of the National Academy of Sciences · 1987 · 2K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

R-Loop Formation Is a Distinctive Characteristic of Unmethylated Human CpG Island Promoters

Paul A. Ginno, Paul C. Lott, Holly C. Christensen et al. · Molecular Cell · 2012 · 929 citations · Full text

Life Sciences, Genetics, Molecular Biology +16

A Topoisomerase IIß-Mediated dsDNA Break Required for Regulated Transcription

Bong‐Gun Ju, Victoria V. Lunyak, Valentina Perissi et al. · Science · 2006 · 842 citations

Life Sciences, Biochemistry, Molecular Biology +17

Human Senataxin Resolves RNA/DNA Hybrids Formed at Transcriptional Pause Sites to Promote Xrn2-Dependent Termination

Konstantina Skourti-Stathaki, Nicholas Proudfoot, Natalia Gromak · Molecular Cell · 2011 · 811 citations · Full text

Life Sciences, Genetics, Molecular Biology +13

R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells

Kefei Yu, Frédéric Chédin, Chih-Lin Hsieh et al. · Nature Immunology · 2003 · 746 citations

Life Sciences, Immunology, Molecular Biology +13