Concepedia

MexAB-OprM specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 6: Exploration of aromatic substituents

Ken‐ichi Yoshida, Kiyoshi Nakayama, Yoshihiro Yokomizo, Masami Ohtsuka, Makoto Takemura, Kazuki Hoshino, Hiroko Kanda, Kenji Namba, Hironobu Nitanai, Jason Z. Zhang,

Bioorganic & Medicinal Chemistry · 2006 · 59 citations · 9 references

DOI

Concepts

References

9

Identification and Characterization of Inhibitors of Multidrug Resistance Efflux Pumps in <i>Pseudomonas aeruginosa</i> : Novel Agents for Combination Therapy

Olga Lomovskaya, Mark S. Warren, Angela Lee et al. · Antimicrobial Agents and Chemotherapy · 2001 · 889 citations · Full text

, , +17

Multiple antibiotic resistance in Pseudomonas aeruginosa: evidence for involvement of an efflux operon

Keith Poole, K A Krebes, Ciarán McNally et al. · Journal of Bacteriology · 1993 · 684 citations · Full text

, , +16

Use of a Genetic Approach To Evaluate the Consequences of Inhibition of Efflux Pumps in <i>Pseudomonas aeruginosa</i>

Olga Lomovskaya, Angela Lee, Kazuki Hoshino et al. · Antimicrobial Agents and Chemotherapy · 1999 · 218 citations · Full text

, , +17

MexAB-OprM-Specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 1: Discovery and early strategies for lead optimization

Kiyoshi Nakayama, Yohei Ishida, Masami Ohtsuka et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 82 citations

, , +17

MexAB-OprM specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 3: Optimization of potency in the pyridopyrimidine series through the application of a pharmacophore model

Kiyoshi Nakayama, Haruko C. Kawato, Jun Watanabe et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 65 citations

, , +14