Animal models of psoriasis: a brief update

Abstract

Abstract Major obstacles to improve our understanding of psoriasis pathogenesis and development of new therapies are in large part due to the absence of accepted and disease‐relevant in‐vivo models. Recent progress in the area of psoriasis disease models include the use of humanized xenotransplantation models and genetically altered mice reflecting psoriasiform pathology. These models provide exciting new insights into disease pathogenesis and will hopefully enable improved pathogenesis‐based drug approaches.