Prevention of occlusive coronary artery thrombosis by prostacyclin infusion in the dog.

An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation

Salvador Moncada, Ryszard J. Gryglewski, S Bunting et al. · Nature · 1976 · 3.6K citations

Medicine, Biochemistry, Pharmacology +16

Prevalence of Total Coronary Occlusion during the Early Hours of Transmural Myocardial Infarction

Marcus A. DeWood, Julie Spores, Robert N. Notske et al. · New England Journal of Medicine · 1980 · 2.7K citations

Medicine, Cardiology, Internal Medicine +12

Platelet aggregation in partially obstructed vessels and its elimination with aspirin.

John D. Folts, E. B. Crowell, George G. Rowe · Circulation · 1976 · 756 citations · Full text

Medicine, Cardiology, Hematology +16

SUCCESSFUL THERAPY OF ADVANCED ARTERIOSCLEROSIS OBLITERANS WITH PROSTACYCLIN

Andrzej Szczeklik, S Skawiński, Rafał Niżankowski et al. · The Lancet · 1979 · 277 citations

Medicine, Cardiology, Pharmacotherapy +3

Circulatory and anti-platelet effects of intravenous prostacyclin in healthy men

Andrzej Szczeklik, Ryszard J. Gryglewski, Rafał Niżankowski et al. · Pharmacological Research Communications · 1978 · 180 citations

Medicine, Hematology, Pharmacology +14