SUCCESSFUL THERAPY OF ADVANCED ARTERIOSCLEROSIS OBLITERANS WITH PROSTACYCLIN

An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation

Salvador Moncada, Ryszard J. Gryglewski, S Bunting et al. · Nature · 1976 · 3.6K citations

Medicine, Biochemistry, Pharmacology +16

Arterial walls are protected against deposition of platelet thrombi by a substance (prostaglandin X) which they make from prostaglandin endoperoxides

Ryszard J. Gryglewski, Stuart Bunting, Salvador Moncada et al. · Prostaglandins · 1976 · 1K citations

Medicine, Cardiology, Hematology +13

MEASUREMENT OF BLOOD-FLOW THROUGH SKELETAL MUSCLE BY INTRAMUSCULAR INJECTION OF XENON-133

Niels A. Lassen, J. Lindbjerg, O. Munck · The Lancet · 1964 · 481 citations

Engineering, Physiology, Biomedical Imaging +7

Generation of prostacyclin by lungs in vivo and its release into the arterial circulation

Ryszard J. Gryglewski, Ryszard Korbut, A. Ocetkiewicz · Nature · 1978 · 374 citations

Medicine, Pharmacology, Pharmacodynamics +5

Comparison of the effects of prostacyclin (PGI2), prostaglandin E1 and D2 on platelet aggregation in different species

Brendan J.R. Whittle, Salvador Moncada, John R. Vane · Prostaglandins · 1978 · 341 citations

Medicine, Biochemistry, Hematology +13