Concepedia

Minocycline inhibits microglial activation and protects nigral cells after 6-hydroxydopamine injection into mouse striatum

Yi He, Stanley H. Appel, Weidong Le

Brain Research · 2001 · 349 citations · 35 references

DOI

Concepts

References

35

Reactive microglia are positive for HLA‐DR in the substantia nigra of Parkinson's and Alzheimer's disease brains

Patrick L. McGeer, Shigeru Itagaki, Barry E. Boyes et al. · Neurology · 1988 · 3K citations

, , +17

Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain

L.J. Lawson, V. Hugh Perry, Pietro Dri et al. · Neuroscience · 1990 · 2K citations

, , +11

Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease

Minghua Chen, Victor Ona, Mingwei Li et al. · Nature Medicine · 2000 · 1.1K citations

, , +17

A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window

Juha Yrjänheikki, Tiina Tikka, Riitta Keinänen et al. · Proceedings of the National Academy of Sciences · 1999 · 1K citations

, , +17

Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia

Juha Yrjänheikki, Riitta Keinänen, M. Pellikka et al. · Proceedings of the National Academy of Sciences · 1998 · 996 citations

, , +12