Concepedia

The protein kinase PKR is required for macrophage apoptosis after activation of Toll-like receptor 4

Jin Mo Park, Kezhong Zhang, Jun‐Li Luo, Shin Maeda, Randal J. Kaufman, Lars Eckmann, Donald G. Guiney, Michael Karin

Nature · 2004 · 358 citations · 23 references

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References

23

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in <i>Tlr4</i> Gene

Alexander Poltorak, Xiaolong He, Irina Smirnova et al. · Science · 1998 · 7.6K citations

, , +17

A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

Ruslan Medzhitov, Paula Preston‐Hurlburt, Charles A. Janeway · Nature · 1997 · 5.5K citations

, , +13

Functional Role of Type I and Type II Interferons in Antiviral Defense

Ulrike Müller, Ulrich Steinhoff, Luiz F. L. Reis et al. · Science · 1994 · 2.5K citations · Full text

, , +15

Unresponsiveness of MyD88-Deficient Mice to Endotoxin

Taro Kawai, Osamu Adachi, Tomohiko Ogawa et al. · Immunity · 1999 · 2.1K citations · Full text

, , +8

Inducible Gene Targeting in Mice

Ralf Kühn, Frieder Schwenk, Michel Aguet et al. · Science · 1995 · 1.9K citations · Full text

, , +14