Concepedia

Sorafenib (BAY 43-9006) inhibits tumor growth and vascularization and induces tumor apoptosis and hypoxia in RCC xenograft models

Yong S. Chang, Jalila Adnane, Pamela A. Trail, Joan Levy, Arris J. Henderson, Dahai Xue, Elizabeth Bortolon, Marina Ichetovkin, Charles Chen, Angela McNabola,

Cancer Chemotherapy and Pharmacology · 2006 · 465 citations · 24 references

DOI

Concepts

References

24

Bevacizumab plus Irinotecan, Fluorouracil, and Leucovorin for Metastatic Colorectal Cancer

Herbert I. Hurwitz, Louis Fehrenbacher, William Novotny et al. · New England Journal of Medicine · 2004 · 11K citations · Full text

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BAY 43-9006 Exhibits Broad Spectrum Oral Antitumor Activity and Targets the RAF/MEK/ERK Pathway and Receptor Tyrosine Kinases Involved in Tumor Progression and Angiogenesis

Scott M. Wilhelm, Christopher Carter, LiYa Tang et al. · Cancer Research · 2004 · 4K citations · Full text

, , +17

A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF

Laura E. Benjamin, Itzhak Hemo, Eli Keshet · Development · 1998 · 1.3K citations

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Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal

Laura E. Benjamin, Dragan Golijanin, Ahuva Itin et al. · Journal of Clinical Investigation · 1999 · 1.2K citations · Full text

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Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors

Gabriele Bergers, Steven Song, Nicole Meyer-Morse et al. · Journal of Clinical Investigation · 2003 · 1.2K citations · Full text

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